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Article

DNA Methylation-Governed Gene Expression in Autoimmune Arthritis

12 Nov 2019

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease hallmarked by progressive and irreversible joint destruction. RA pathogenesis is a T cell-regulated and B cell-mediated process in which activated lymphocyte-produced chemokines and cytokines promote leukocyte infiltration that ultimately leads to destruction of the joints. There is an obvious need to discover new drugs for RA treatment that...

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PMID: 31718084
DOI: 10.3390/ijms20225646

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