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Article

Methylene tetrahydrofolate reductase, transforming growth factor-β1 and lymphotoxin-α genes polymorphisms and susceptibility to rheumatoid arthritis.

Revista brasileira de reumatologia - 1 Jan 2000

Shaker Olfat G, Alnoury Amina M, Hegazy Gehan A, El Haddad Hemmat E, Sayed Safaa, Hamdy Ahmed

Abstract excerpt

BACKGROUND: Rheumatoid arthritis is a widely prevalent autoimmune disorder with suggested genetic predisposition. OBJECTIVES: The aim of this study is to detect the pattern of genetic polymorphism of methylene tetrahydrofolate reductase (MTHFR C677 T and A1298 C), transforming growth factor-β1 (TGF-β1 T869 C) and lymphotoxin-α (LT-α A252G) in patients having rheumatoid arthritis and correlate these patterns to...

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Source

Identifiers

PMID: 27692391
DOI: 10.1016/j.rbre.2016.04.002

Genes

MTHFR
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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