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Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis

6 Dec 2022

Abstract excerpt

Objectives HTR2A is previously identified as a susceptibility gene for rheumatoid arthritis (RA). In this study, we performed the association analysis between DNA methylation of HTR2A with RA within peripheral blood samples. Methods We enrolled peripheral blood samples from 235 patients with RA, 30 osteoarthritis (OA) patients, and 30 healthy controls. The DNA methylation levels of about 218 bp from chr13:...

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PMID: 36561742
DOI: 10.3389/fimmu.2022.1054451

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