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Mitochondria-Related Gene BDH1 Implicated in Myopia Risk via Methylation-Regulated Expression: An Integrative Summary-Data Mendelian Randomization Study.

Translational vision science & technology - 5 Jan 2026

Peng Shiming, Deng Hongwei, Tao Zhengyang, Chen Jing, Kang Zefeng

Abstract excerpt

Purpose: The purpose of this study was to prioritize mitochondria-related causal genes (MRGs) involved in myopia by integrating MRGs-related methylation quantitative trait loci (mQTL), expression quantitative trait loci (eQTL), and protein quantitative trait loci (pQTL) data with myopia genome-wide association study (GWAS) data. Methods: UK Biobank data were utilized for discovery, and FinnGen data for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41533846
DOI: 10.1167/tvst.15.1.7
PMCID: PMC12786396

Genes

BDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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