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Article

Association of mitochondrial DNA variation with high myopia in a Han Chinese population.

Molecular genetics and genomics : MGG - 1 Sept 2023

Xing Shilai, Jiang Siyi, Wang Siyu, Lin Peng, Sun Haojun, Peng Hui, Yang Jiaying, Kong Hengte, Wang Sheng, Bai Qingshi, Qiu Ruowen, Dai Wei, Yuan Jian, Ma Yunlong, Yu Xiaoguang, Yao Yinghao, Su Jianzhong

Abstract excerpt

High myopia (HM), which is characterized by oxidative stress, is one of the leading causes of visual impairment and blindness across the world. Family and population genetic studies have uncovered nuclear-genome variants in proteins functioned in the mitochondria. However, whether mitochondrial DNA mutations are involved in HM remains unexplored. Here, we performed the first large-scale whole-mitochondrial genome...

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Identifiers

PMID: 37277661
DOI: 10.1007/s00438-023-02036-y
PMCID: PMC10363046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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