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MODIG: An Attention Mechanism-Based Approach to Cancer Driver Gene Identification.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025

Zhao Wenyi, Zhou Zhan

Abstract excerpt

Identifying genes that play a causal role in carcinogenesis remains one of the major challenges in cancer biology. With the accumulation of high-throughput multi-omics data over decades, it has become a great challenge to effectively integrate these data into the identification of cancer driver genes. Here, we propose MODIG, a graph attention network (GAT)-based framework, to identify cancer driver genes by...

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PMID: 40779114
DOI: 10.1007/978-1-0716-4566-6_13

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