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Article

Preoperative Detection of Dual TERT Promoter Mutations in Thyroid Cancer: A Case Series.

Diagnostic cytopathology - 1 Apr 2026

Harari Amir, Huiras Jennifer, Chen Yang, Alshalalfa Mohammed, Hao Yangyang, Klopper Joshua P, Kloos Richard T, Vazquez Bianca J

Abstract excerpt

Telomerase reverse transcriptase promoter (TERTp) mutations are associated with aggressive thyroid cancer and are most frequently found in anaplastic and poorly differentiated thyroid cancer. Pre-operative thyroid nodule molecular testing can detect TERTp, denoting a high risk of malignancy and possible aggressive clinical features such as extrathyroidal extension, regional lymph node metastases, and distant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41524254
DOI: 10.1002/dc.70058
PMCID: PMC12954826

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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