Article
Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAF(V600E) Mutation-Prevalent Population.
Thyroid : official journal of the American Thyroid Association - 1 Jul 2016
Lee Seung Eun, Hwang Tae Sook, Choi Yoon-La, Han Hye Seung, Kim Wan Seop, Jang Min Hye, Kim Suk Kyeong, Yang Jung Hyun
Abstract excerpt
BACKGROUND: The role of telomerase reverse transcriptase (TERT) promoter mutations in differentiated thyroid cancer has been well established. These mutations have a significantly higher prevalence in aggressive thyroid tumors, including widely invasive oncocytic carcinomas, poorly differentiated carcinomas, and anaplastic thyroid carcinomas. Interestingly, in some studies, TERT mutations were found to be more...
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