Article
Disease-Specific and Histological Outcomes of Preoperative TERT Promoter Mutation Detected in Isolation or in Combination with Other Mutations in Thyroid Neoplasms.
Thyroid : official journal of the American Thyroid Association - 1 Oct 2025
Calcaterra Michael, Sada Alaa, Karslioglu-French Esra, Morariu Elena M, McCoy Kelly L, Ramonell Kimberly M, Kurtom Saba, Ohori N Paul, Chiosea Simion I, Seethala Raja R, Carty Sally E, Nikiforova Marina N, Nikiforov Yuri E, Yip Linwah
Abstract excerpt
Background: TERT promoter mutations in thyroid cancer are associated with aggressive disease, including recurrence, distant metastasis, and disease-related mortality. We aim to assess histological and disease-related outcomes when TERT mutation is detected alone or with other alterations during preoperative testing. Methods: A retrospective, single-institution study was performed, including all adult patients...
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