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Article

TERT promoter mutations in thyroid cancer.

Endocrine-related cancer - 1 Mar 2016

Liu Rengyun, Xing Mingzhao

Abstract excerpt

The 2013 discovery of Telomerase reverse transcriptase (TERT) promoter mutations chr5, 1,295,228 C>T (C228T) and 1,295,250 C>T (C250T) in thyroid cancer represents an important event in the thyroid cancer field and much progress has occurred since then. This article provides a comprehensive review of this exciting new thyroid cancer field. The oncogenic role of TERT promoter mutations involves their creation of...

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Topics

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Share to BRAF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26733501
DOI: 10.1530/ERC-15-0533
PMCID: PMC4750651

Genes

TERT
BRAF

Variants

Provenance

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