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Article

Genetics and pathogenesis of chronic pancreatitis: the 2012 update.

Clinics and research in hepatology and gastroenterology - 1 Aug 2012

Chen Jian-Min, Férec Claude

Abstract excerpt

Chronic pancreatitis is a persistent inflammation of the pancreas that results in irreversible morphological changes and impairment of both exocrine and endocrine functions. Genetic studies of the disease over the past 15 years have led to the identification of four firmly established susceptibility genes namely PRSS1, SPNIK1, CTRC and CFTR. Our previously published review (Chen and Férec. Annu Rev Genomics Hum...

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Source

Identifiers

PMID: 22749696
DOI: 10.1016/j.clinre.2012.05.003

Genes

CFTR
CTRC
PRSS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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