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Article

Comparison of the differentially enriched mutations/pathways between stage II and stage IV dMMR/MSI-H colorectal cancer.

Science progress - 1 Jan 2026

Han Chun, Ye Sisi, Li Juan, Qiao Qian, Bai Li, Zhang Tingting

Abstract excerpt

ObjectiveColorectal cancer (CRC) patients with high microsatellite instability (MSI-H) and mismatch repair deficiency (dMMR) had heterogeneous pathology and distinct prognoses. This study aimed to examine the difference in the gene expression profile of dMMR/MSI-H CRC patients with different disease stages and explore the different molecular mechanisms of disease progression.MethodsA total of 47 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41505340
DOI: 10.1177/00368504251412580
PMCID: PMC12783548

Genes

EPHA3
FGFR1
MTHFR
PDGFRB
PTPN13
RAD50
SMAD3
SMARCA4
STK11
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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