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Associations of NEUROD2 polymorphisms and change of cognitive dysfunctions in schizophrenia and schizoaffective disorder after eight weeks of antipsychotic treatment.

Cognitive neuropsychiatry - 1 Jul 2017

Spellmann Ilja, Riedel Michael, Städtler Julia, Zill Peter, Obermeier Michael, Cerovecki Anja, Dehning Sandra, Schennach Rebecca, Epple Maria, Opgen-Rhein Markus, Müller Norbert, Bondy Brigitta, Möller Hans-Jürgen, Musil Richard

Abstract excerpt

INTRODUCTION: NEUROD2 is a neurospecific helix-loop-helix transcription factor which has an impact on the regulation of glutamatergic and GABAergic genes. We investigated an association of NEUROD2 with neurocognitive dysfunctions in schizophrenia and schizoaffective disorder patients before and during treatment with different second-generation antipsychotics. METHODS: Patients were genotyped for four different...

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Identifiers

PMID: 28470106
DOI: 10.1080/13546805.2017.1322502

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NEUROD2

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