Article
Elevated antisaccade error rate as an intermediate phenotype for psychosis across diagnostic categories.
Schizophrenia bulletin - 1 Sept 2014
Reilly James L, Frankovich Kyle, Hill Scot, Gershon Elliot S, Keefe Richard S E, Keshavan Matcheri S, Pearlson Godfrey D, Tamminga Carol A, Sweeney John A
Abstract excerpt
BACKGROUND: Elevated antisaccade error rate, reflecting problems with inhibitory behavioral control, is a promising intermediate phenotype for schizophrenia. Here, we consider whether it marks liability across psychotic disorders via common or different neurophysiological mechanisms and whether it represents a neurocognitive risk indicator apart from the generalized cognitive deficit. METHODS: Schizophrenia (n =...
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