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Article

Thirty-Year Risk of Cardiovascular Disease Among Healthy Women According to Clinical Thresholds of Lipoprotein(a).

JAMA cardiology - 1 Feb 2026

Nordestgaard Ask Tybjærg, Chasman Daniel I, Moorthy Vinayaga, Kraaijenhof Jordan M, Cook Nancy R, Lee I-Min, Buring Julie E, Ridker Paul M

Abstract excerpt

Importance: Elevated lipoprotein(a) predicts high risk of cardiovascular disease among a modest proportion of healthy individuals, an issue that complicates screening guidelines. Objective: To examine spline models, clinical thresholds, and percentiles of baseline lipoprotein(a) levels as 30-year determinants of cardiovascular risk. Design, Setting, and Participants: This cohort study was conducted among female...

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Identifiers

PMID: 41499112
DOI: 10.1001/jamacardio.2025.5043
PMCID: PMC12780984

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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