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Beyond Cholesterol: A Comprehensive Review and Disease Architecture Reassessment of Lipid and Lipoprotein Biomarkers in ASCVD

2026-07-01

Abstract excerpt

<h4>Background: </h4> Over the past six decades, the lipid-centric paradigm has guided the understanding, prevention, and treatment of atherosclerotic cardiovascular disease (ASCVD). As limitations of earlier lipid measurements became apparent, progressively more sophisticated biomarkers—including LDL-C, non-HDL-C, apolipoprotein B (ApoB), LDL particle number (LDL-P), small dense LDL (sdLDL), oxidized LDL (oxLDL),...

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Literature Corpus work
6b30fa23-a61d-5a2d-822e-30128452b816
DOI
10.20944/preprints202607.0008.v1
Open publication

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