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RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury

7 Aug 2023

Abstract excerpt

Acute lung injury (ALI) is a significant contributor to the development of acute respiratory distress syndrome (ARDS), which is a severe clinical condition associated with high morbidity and mortality. 1 It is increasingly evident that preserving mitochondrial health in alveolar epithelial cells holds great therapeutic potential for ARDS. 2 Mitophagy, a cellular process aimed at maintaining mitochondrial health,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37544975
DOI: 10.1038/s41392-023-01520-6

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