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Article

Obesity, birth weight, and lifestyle factors for frailty: a Mendelian randomization study.

Aging - 12 Dec 2023

Gu Yingzhen, Li Zuozhi, Dang Aimin, Zhang Wei, Liu Jinxing, Han Xiaorong, Li Yifan, Lv Naqiang

Abstract excerpt

Obesity, birth weight and lifestyle factors have been found associated with the risk of frailty in observational studies, but whether these associations are causal is uncertain. We conducted a two-sample Mendelian randomization study to investigate the associations. Genetic instruments associated with the exposures at the genome-wide significance level (p < 5 × 10-8) were selected from corresponding genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38095641
DOI: 10.18632/aging.205290
PMCID: PMC10756094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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