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Article

Plasma lipid subspecies and Alzheimer's disease: genetic evidence for risk and protection.

QJM : monthly journal of the Association of Physicians - 1 Jul 2026

Zhang Xiaoling, Xie Guomin, Zhao Cui, Lv Zhongyue

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder with lipid metabolism implicated in its pathogenesis. The potentially causal relationship between specific lipid subtypes and AD remains unclear due to confounding factors. This study employs Mendelian randomization (MR) to investigate the genetic associations between plasma lipid subtypes and AD risk. METHODS: A MR method was employed utilizing...

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PMID: 41490095
DOI: 10.1093/qjmed/hcag006

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PC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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