Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of lipid species in Alzheimer's disease onset: A comprehensive Mendelian randomization analysis.

Brain research - 1 Jan 2025

Wang Wen, Xia HongLian

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) remains a significant global health challenge, with its etiology intricately linked to a variety of genetic and environmental factors. Among these, lipid metabolism has been hypothesized to play a crucial role, though the causal pathways remain inadequately elucidated. This study aims to employ Mendelian Randomization (MR) to unravel the potential causal relationships between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Metabolism

Share to Lipids

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39278307
DOI: 10.1016/j.brainres.2024.149238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of lipid species in Alzheimer's disease onset: A comprehensive Mendelian randomization analysis.PMID 39278307Read ↗

Plasma lipid subspecies and Alzheimer's disease: genetic evidence for risk and protection.Semantic proximity Read ↗

Systematic evaluation of multifactorial causal associations for Alzheimer's disease and an interactive platform based on Mendelian randomization analysis——MRADSemantic proximity Read ↗

Systematic evaluation of multifactorial causal associations for Alzheimer's disease and an interactive platform MRAD developed based on Mendelian randomization analysis.Semantic proximity Read ↗

Investigating Causal Relations Between Circulating Metabolites and Alzheimer’s Diseases: A Mendelian Randomization StudySemantic proximity Read ↗

The role of cerebrospinal fluid metabolites in mediating the impact of lipids on Late-Onset Alzheimer's Disease: a two-step mendelian randomization analysis.Semantic proximity Read ↗

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.Semantic proximity Read ↗

Investigating Causal Relations Between Circulating Metabolites and Alzheimer's Disease: A Mendelian Randomization Study.Semantic proximity Read ↗

Exploring the causal effects of serum lipids and lipidomes on lewy body dementia: a Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer's disease.Semantic proximity Read ↗

Multidimensional plasma lipid composition and its causal association with type 2 diabetes mellitus: A Mendelian randomization study.Semantic proximity Read ↗

The Causal Relationship Between Circulating Metabolites and the Risk of Atopic Dermatitis: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Causal relationships between Alzheimer's disease and metabolic dysfunction associated with fatty liver disease: insights from bidirectional network Mendelian Randomization analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.