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Article

Investigating Causal Relations Between Circulating Metabolites and Alzheimer's Disease: A Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Huang Shu-Yi, Yang Yu-Xiang, Zhang Ya-Ru, Kuo Kevin, Li Hong-Qi, Shen Xue-Ning, Chen Shi-Dong, Chen Ke-Liang, Dong Qiang, Tan Lan, Yu Jin-Tai

Abstract excerpt

BACKGROUND: Metabolomics is a promising approach that can be used to understand pathophysiological pathways of Alzheimer's disease (AD). However, the causal relationships between metabolism and AD are poorly understood. OBJECTIVE: We aimed to investigate the causal association between circulating metabolites and risk of AD through two-sample Mendelian randomization (MR) approach. METHODS: Genetic associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35275550
DOI: 10.3233/JAD-220050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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