Article
Genomics of Long-Term Complications of Childhood Leukemia: Rationale and Design of the GenLEA Study.
Pediatric blood & cancer - 1 Mar 2026
Veneziano-Broccia Mathilde, Michel Gerard, Dalle Jean-Hugues, Deleuze Jean-François, Olaso Robert, Munsch Gaëlle, Germain Marine, Meguerditchian Caroline, Ducassou Stéphane, Domenech Carine, Tabone Marie-Dominique, Auquier Pascal, Berbis Julie, Tregouet David-Alexandre, Saultier Paul
Abstract excerpt
BACKGROUND: Survivors of childhood acute leukemia are at risk of long-term treatment-related complications, but the role of genetic susceptibility remains unclear. We describe here the GenLEA project, which was established to investigate genetic determinants of long-term complications. METHODS: GenLEA builds on the French LEA cohort, which prospectively follows acute leukemia survivors since 2004 through...
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