Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of genetic biomarkers on cardiac diseases in childhood cancer survivors: a systematic review.

The pharmacogenomics journal - 24 May 2025

Aba Naïla, Ducos Claire, Morel Eric, El Fayech Chiraz, Fresneau Brice, de Vathaire Florent, Le Teuff Gwénaël, Haddy Nadia

Abstract excerpt

Childhood cancer survivors (CCS) often suffer from cardiac disease (CD) after treatment that included anthracycline and radiotherapy involving the heart. However, the variability in CD occurrence cannot be explained solely by these treatments, suggesting the existence of genetic predisposition. We conducted a systematic review searching on Medline-PubMed and Scopus, to identify studies reporting associations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthracyclines
Share to Cancer Survivors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CCS gene

Share to Genetic Markers

Share to Genetic Predisposition to Disease

Share to Heart Diseases

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 40413218
DOI: 10.1038/s41397-025-00369-y
PMCID: PMC12103300

Genes

CCS
P2RX7
RARG
SLC28A3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of genetic biomarkers on cardiac diseases in childhood cancer survivors: a systematic review.PMID 40413218Read ↗

Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.Semantic proximity Read ↗

Predicting the 10-year risk of cardiomyopathy in long-term survivors of childhood cancer: a report from the St. Jude Lifetime Cohort and the Childhood Cancer Survivor StudySemantic proximity Read ↗

Genome-Wide Association Study Identifies ROBO2 as a Novel Susceptibility Gene for Anthracycline-Related Cardiomyopathy in Childhood Cancer SurvivorsSemantic proximity Read ↗

Genetic Variants Associated with Therapy-Related Cardiomyopathy among Childhood Cancer Survivors of African Ancestry.Semantic proximity Read ↗

Risk of anthracycline-induced cardiac dysfunction in adolescent and young adult (AYA) cancer survivors: role of genetic susceptibility loci.Semantic proximity Read ↗

The genetic underpinnings of anthracycline-induced cardiomyopathy predisposition.Semantic proximity Read ↗

Genetic Susceptibility and Mechanisms Underlying the Pathogenesis of Anthracycline-Associated Cardiotoxicity.Semantic proximity Read ↗

Possible roles of genetic variations in chemotherapy related cardiotoxicity in pediatric acute lymphoblastic leukemia and osteosarcoma.Semantic proximity Read ↗

Common genetic predisposition for heart failure and cancer.Semantic proximity Read ↗

Genetic factors in anthracycline-induced cardiotoxicity in patients treated for pediatric cancer.Semantic proximity Read ↗

Genetic susceptibility to anthracycline-related congestive heart failure in survivors of haematopoietic cell transplantation.Semantic proximity Read ↗

Chemotherapy-Related Cardiac Dysfunction: A Systematic Review of Genetic Variants Modulating Individual Risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.