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Article

Dysregulation of ERAD and Stress Response Proteins by V493F FTO Over-expression: A Proteomic Perspective.

In vivo (Athens, Greece) - 1 Jan 2026

Kanli Aylin

Abstract excerpt

BACKGROUND/AIM: Demethylase fat mass and obesity-related protein (FTO), which belongs to the AlkB homologous (ABH) family, is associated with various neurological diseases, cancer, and obesity. This protein, which contains many structurally and functionally different regions, contains a COOH-terminal domain whose function, unlike other ABH members, is not fully understood. This study aimed to investigate the...

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Topics

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Endoplasmic Reticulum-Associated Degradation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proteome

Share to Proteomics

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Stress, Physiological

Source

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Identifiers

PMID: 41482413
DOI: 10.21873/invivo.14188
PMCID: PMC12764248

Genes

FTO
ARHGDIA
HSPA4
PCNA
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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