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Article

The biology of FTO: from nucleic acid demethylase to amino acid sensor.

Diabetologia - 1 Oct 2013

Gulati Pawan, Yeo Giles S H

Abstract excerpt

Genome-wide association studies have revealed that single-nucleotide polymorphisms in the first intron of the gene encoding fat mass and obesity-associated protein (FTO) are robustly associated with BMI and obesity. Subsequently, this association with body weight, which is replicable across multiple populations and different age groups, has been unequivocally linked to increased food intake. Although evidence...

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Identifiers

PMID: 23896822
DOI: 10.1007/s00125-013-2999-5
PMCID: PMC3764322

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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