Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between ABCG2 polymorphisms and allopurinol response in gout patients: a systematic review and meta-analysis.

Pharmacogenomics - 1 Jan 2025

Lee Jia Wen, Badrul Hisham Muhammad Danish, Low Xin Yee, Teh L K

Abstract excerpt

AIM: This systematic review and meta-analysis aimed to investigate the association between ABCG2 polymorphisms and allopurinol response in gout patients. METHODS: A comprehensive search of Scopus, PubMed, Web of Science, EBSCOhost, and the Clinical Pharmacogenomic Resource was conducted for observational studies up to May 2025. Two authors independently screened studies, extracted data, and assessed study quality...

Topics

Join the communities discussing this publication.

Allopurinol
ATP Binding Cassette Transporter, Subfamily G, Member 2
ABCG2 gene
Gout
Gout Suppressants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Proteins

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 41472487
DOI: 10.1080/14622416.2025.2609364
PMCID: PMC12915791

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between ABCG2 polymorphisms and allopurinol response in gout patients: a systematic review and meta-analysis.PMID 41472487Read ↗

Association between ABCG2 rs2231142 and poor response to allopurinol: replication and meta-analysis.Semantic proximity Read ↗

Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.Semantic proximity Read ↗

ABCG2 loss-of-function polymorphism predicts poor response to allopurinol in patients with gout.Semantic proximity Read ↗

The association between the polymorphism rs2231142 in the ABCG2 gene and gout risk: a meta-analysis.Semantic proximity Read ↗

Genome‐Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for AllopurinolSemantic proximity Read ↗

A systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level.Semantic proximity Read ↗

The ABCG2 gene Q141K polymorphism contributes to an increased risk of gout: a meta-analysis of 2185 cases.Semantic proximity Read ↗

Association of rare and common genetic variants in MOCOS with inadequate response to allopurinol.Semantic proximity Read ↗

The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis.Semantic proximity Read ↗

ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approachesSemantic proximity Read ↗

Pharmacogenetic Perspective for Optimal Gout ManagementSemantic proximity Read ↗

The genetics of gout: towards personalised medicine?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.