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Article

Genetic Association Between Polymyositis/Dermatomyositis and Epilepsy: Insights From Mendelian Randomization and Bioinformatic Analyses.

Brain and behavior - 1 Jan 2026

Liu Ying, Yu Yuhang, Fang Chulong, Wu Qingzhong, Ou Lingli, Xiao Jianhao, Duan Kui, Jiang Ting, Ye Lan, Hu Xiao, Feng Zhanhui

Abstract excerpt

BACKGROUND: Idiopathic inflammatory myositis (IIM), comprising polymyositis (PM) and dermatomyositis (DM), is a collective term for immune-mediated diseases characterized by skeletal muscle inflammation. Emerging evidence points to an increased incidence of epilepsy in patients with PM/DM. However, the causality and underlying mechanisms behind this association are unclear. Our study aimed to explore the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41466027
DOI: 10.1002/brb3.71148
PMCID: PMC12748525

Genes

ATF6B
IER3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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