Article
Exploring correlations between immune cell phenotypes and the risk of epilepsy: A bidirectional Mendelian randomization study.
Epilepsy & behavior : E&B - 1 Aug 2024
Chen Zhiqing, Sun Huaiyu, Zhang Wuqiong, Hou Shuai, Yang Xi, Lin Jingqi, Ma Xiaohui, Meng Hongmei
Abstract excerpt
BACKGROUND: Neuroinflammation plays an important pathophysiological role in epilepsy; however, the precise connection between immune cells and epilepsy remains unclear. This study used Mendelian randomization (MR) to analyze the causal relationship between 731 immune cell traits and epilepsy. METHODS: Based on data from a genome-wide association study (GWAS), a bidirectional two-sample MR analysis was conducted...
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