Article
Evaluation of clonality in lentigo maligna.
The Journal of investigative dermatology - 1 Jul 2026
Lim Sophie Soyeon, Zhao Peinan, Wong Nicholas C, Szeto Pacman, Wilson Trevor, Mitchell Helen, Vergara Ismael A, Bruscino-Raiola Francesco, McCormack Christopher, Webb Angela, Henderson Michael A, McLean Catriona, Papenfuss Anthony T, Mar Victoria, Shackleton Mark
Abstract excerpt
Lentigo maligna (LM), a type of in situ melanoma, has a high rate of local recurrence after surgical resection. Although recurrences might represent inadequately excised incident LMs, apparent recurrences could be new primary LMs developing from distinct melanocytic clones in the same UVR-damaged anatomical region. Because distinguishing these possibilities has implications for patient management, we tested...
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