Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.

Scientific reports - 13 Dec 2019

Melnikova Larisa, Molodina Varvara, Erokhin Maksim, Georgiev Pavel, Golovnin Anton

Abstract excerpt

Suppressor of Hairy-wing [Su(Hw)] is one of the best characterized architectural proteins in Drosophila and recruits the CP190 and Mod(mdg4)-67.2 proteins to chromatin, where they form a well-known insulator complex. Recently, HP1 and insulator partner protein 1 (HIPP1), a homolog of the human co-repressor Chromodomain Y-Like (CDYL), was identified as a new partner for Su(Hw). Here, we performed a detailed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Microtubule-Associated Proteins

Share to Nuclear Proteins

Share to Protein Domains

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 31836797
DOI: 10.1038/s41598-019-55617-6
PMCID: PMC6911044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.PMID 31836797Read ↗

A Drosophila insulator interacting protein suppresses enhancer-blocking function and modulates replication timing.Semantic proximity Read ↗

Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in Drosophila.Semantic proximity Read ↗

Interactions between BTB domain of CP190 and two adjacent regions in Su(Hw) are required for the insulator complex formation.Semantic proximity Read ↗

The centrosomal protein CP190 is a component of the gypsy chromatin insulator.Semantic proximity Read ↗

Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements.Semantic proximity Read ↗

The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.Semantic proximity Read ↗

EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.Semantic proximity Read ↗

Mutations in the Insulator Protein Suppressor of Hairy Wing Induce Genome InstabilitySemantic proximity Read ↗

Mutations in the insulator protein Suppressor of Hairy wing induce genome instability.Semantic proximity Read ↗

The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning.Semantic proximity Read ↗

Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex.Semantic proximity Read ↗

Characterization of functional domains of the su(Hw) protein that mediate the silencing effect of mod(mdg4) mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.