Article
New insights on underlying shared genetic architectures and causality of underweight and depression in East Asian populations.
Journal of affective disorders - 1 Jul 2025
Chen Ming, Xiao Zhen, Wang Yueya, Ou Wanqi, Hou Cailan, Huang Hao-Zhang
Abstract excerpt
BACKGROUND: Extensive evidence links a lower body mass index (BMI) to higher odds of depression in individuals of East Asian ancestry, differing from patterns observed in European populations. However, the shared genetic etiology underlying underweight and depression remains unclear in East Asian populations. METHOD: Utilizing large-scale genome-wide association study (GWAS) data, we investigated the shared...
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