Accuracy of the Phenotypic 1G Test to Detect Mycobacterium tuberculosis and Drug Resistance From Sputa in the US-Mexico Border.

doi:10.1093/infdis/jiaf638

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Article

Accuracy of the Phenotypic 1G Test to Detect Mycobacterium tuberculosis and Drug Resistance From Sputa in the US-Mexico Border.

The Journal of infectious diseases - 29 Apr 2026

Aguirre Mia, Ayala Doris, Garcia Juan Ignacio, Martinez-Lopez Yoscelina E, Hicks Amberlee D, Chacon Nadine, Gay-Cobb Ashley, Schami Alyssa, Zavala-Perez Selena, Dominguez-Trejo Ilse A, Cruz-Gonzalez America M, Loera-Salazar Raul, Rodríguez-Herrera Javier E, Garcia-Oropesa Esperanza M, Lee Miryoung, Rendón Adrian, Wang Shu-Hua, Yotebieng Marcel, Evans Carlton A, Torrelles Jordi B, Restrepo Blanca I

Abstract excerpt

BACKGROUND: With >10 million new tuberculosis (TB) cases per year, a limitation to TB control is the lack of simple and accurate tests for diagnosis and drug susceptibility testing (DST) in endemic regions. We evaluated the accuracy of the first-generation, low-complexity phenotypic TB test (1G test), designed for simultaneous Mycobacterium tuberculosis (Mtb) detection and resistance to isoniazid, rifampicin, and...

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PMID: 41432525
DOI: 10.1093/infdis/jiaf638
PMCID: PMC12853293

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