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Article

Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.

The New England journal of medicine - 14 Sept 2017

Xie Yingda L, Chakravorty Soumitesh, Armstrong Derek T, Hall Sandra L, Via Laura E, Song Taeksun, Yuan Xing, Mo Xiaoying, Zhu Hong, Xu Peng, Gao Qian, Lee Myungsun, Lee Jongseok, Smith Laura E, Chen Ray Y, Joh Joon Sung, Cho YoungSoo, Liu Xin, Ruan Xianglin, Liang Lili, Dharan Nila, Cho Sang-Nae, Barry Clifton E, Ellner Jerrold J, Dorman Susan E, Alland David

Abstract excerpt

BACKGROUND: Fluoroquinolones and second-line injectable drugs are the backbone of treatment regimens for multidrug-resistant tuberculosis, and resistance to these drugs defines extensively drug-resistant tuberculosis. We assessed the accuracy of an automated, cartridge-based molecular assay for the detection, directly from sputum specimens, of Mycobacterium tuberculosis with resistance to fluoroquinolones,...

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Identifiers

PMID: 28902596
DOI: 10.1056/NEJMoa1614915
PMCID: PMC5727572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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