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Article

Diagnostics and new treatment regimens for TB: can the Xpert MTB/XDR assay fill the gap for fluoroquinolone testing?

Journal of clinical microbiology - 8 Oct 2025

Armstrong Derek T, Baird Emma C E, Pretty Logan, D'Agostino Karen, Schwartz Matthew, Campódonico Victoria L, Parrish Nicole

Abstract excerpt

Rapid diagnosis of resistance-conferring mutations to antibiotics used for the treatment of tuberculosis (TB) is critical for patient care and public health control efforts. Prior guidelines included the use of fluoroquinolones (FQs) for the treatment of drug-resistant TB, including multidrug-resistant TB, pre-extensively drug-resistant TB, and extensively drug-resistant TB. More recently, a short-course regimen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40899881
DOI: 10.1128/jcm.00643-25
PMCID: PMC12509795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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