Article
Modifiable lifestyle factors and genetic risk of obesity in Indians.
Scientific reports - 8 Dec 2025
Hassanin Emadeldin, Kalapala Rakesh, Jagtap Nitin, Vishnubhotla Ravikanth, Andhi Nikhilesh, Mamidi Sandeep, Vyshnavi Shree, Jilla Srikanth, Samudrala Mithil, Shriya P Shravani, Chawla Kamaldeep, Maj Carlo, May Patrick, Bobbili Dheeraj Reddy, Reddy D Nageshwar
Abstract excerpt
This study investigates whether sustained adherence to a healthy lifestyle is associated with lower obesity risk among individuals of Indian ancestry who have a high polygenic risk score (PRS) for body mass index (BMI). For the purposes of this research, a health-promoting lifestyle is defined by routine physical activity, non-smoking or minimal smoking behavior, and adherence to a balanced diet. We analyzed two...
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