Article
Lifestyle factors and fetal and childhood origins of type 2 diabetes: a prospective study of Chinese and European adults.
The American journal of clinical nutrition - 4 Mar 2022
Wang Wenxiu, Lv Jun, Yu Canqing, Guo Yu, Pei Pei, Zhuang Zhenhuang, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Du Huaidong, Wu Xianping, Chen Junshi, Chen Zhengming, Clarke Robert, Huang Tao, Li Liming
Abstract excerpt
BACKGROUND: Early-life development plays a key role in adult type 2 diabetes (T2D), but the extent to which this can be attenuated by lifestyle is unknown. OBJECTIVES: The aim was to investigate the independent relevance of genetic predisposition to low birth weight and childhood obesity for T2D, and their attenuation, by adherence to a healthy lifestyle in adulthood. METHODS: Genetic risk scores (GRSs) were...
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