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Article

Integrated network propagation identifies prognostic metabolic signatures in acute myeloid leukemia.

Journal of translational medicine - 3 Dec 2025

Song Jong Keon, Kim Hyery, Hwang Sang-Hyun

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML), a biologically heterogeneous malignancy, requires improved prognostic models, particularly for patients with intermediate-risk profiles and lacking definitive genetic markers. Therefore, this study aims to identify biologically coherent and clinically informative gene signatures using a novel prognostic modeling approach integrating gene expression profiles with...

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Source

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Identifiers

PMID: 41340131
DOI: 10.1186/s12967-025-07524-w
PMCID: PMC12903322

Genes

IDH1
IDH2
ARL6IP5
CSK
ECHS1
ENO1
ETFB
FLT3
G6PD
HS3ST3B1
IL4I1
NDST3
NDUFS8
NPM1
PLA2G4A
PLD1
PTP4A3
SDHA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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