Article

Network-Based Stratification Refines Stratification of Intermediate-Risk Acute Myeloid Leukemia Samples

2025-07-05

Abstract excerpt

The European LeukemiaNet (ELN) risk stratification of acute myeloid leukemia (AML) uses genetic and molecular markers to categorize patients. However, disease heterogeneity, particularly in the intermediate-risk group, complicates stratification. Ideker et al. developed the Network-Based Stratification (NBS) method, combining protein network analysis and mutation profiling via machine learning. We applied NBS to i...

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Literature Corpus work: 1e2edaf2-c3f3-5f89-a92e-6ed027c9bd8a
DOI: 10.1101/2025.07.04.25330879

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