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Prioritizing risk genes as novel stratification biomarkers for acute monocytic leukemia by integrative analysis

30 Jun 2022

Abstract excerpt

Acute myeloid leukemia (AML) is a blood cancer with high heterogeneity and stratified as M0-M7 subtypes in the French-American-British (FAB) diagnosis system. Improved diagnosis with leverage of key molecular inputs will assist precisive medicine. Through deep-analyzing the transcriptomic data and mutations of AML, we report that a modern clustering algorithm, t-distributed Stochastic Neighbor Embedding (t-SNE),...

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PMID: 35771283
DOI: 10.1007/s12672-022-00516-y

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