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A 4‐gene prognostic index for enhancing acute myeloid leukaemia survival prediction

23 Apr 2024

Abstract excerpt

Despite advancements in utilizing genetic markers to enhance acute myeloid leukaemia (AML) outcome prediction, significant disease heterogeneity persists, hindering clinical management. To refine survival predictions, we assessed the transcriptome of non-acute promyelocytic leukaemia chemotherapy-treated AML patients from five cohorts (n = 975). This led to the identification of a 4-gene prognostic index (4-PI)...

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PMID: 38651345
DOI: 10.1111/bjh.19472

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