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The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML

29 May 2021

Abstract excerpt

BACKGROUND: The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles correlating with prognostic genetic abnormalities by WGCNA. METHODS: ≥ 0.4, p < 0.01). ORA detected the enriched pathways for the key co-expression modules. The patients in TCGA cohort were...

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PMID: 34051812
DOI: 10.1186/s12967-021-02914-2

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