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Article

Identifying the plasma metabolome responsible for mediating immune cell action in severe COVID-19: a Mendelian randomization investigation.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Zhang Yixia, Hua Jie, Chen Liang

Abstract excerpt

Introduction: The immune response regulates the severity of COVID-19 (sCOVID-19). This study examined the cause-and-effect relationship between immune cell traits (ICTs) and the risk of severe COVID-19. Additionally, we discovered the potential role of plasma metabolome in modulating this risk. Methods: Employing data from a genome-wide association study (GWAS), we conducted a two-sample Mendelian randomization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39224704
DOI: 10.3389/fcimb.2024.1393432
PMCID: PMC11366714

Genes

CD27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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