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Article

Plasma metabolites as mediators in immune cell-pancreatic cancer risk: insights from Mendelian randomization.

Frontiers in immunology - 1 Jan 2024

Zhang Ke, Zhu Jie, Wang Peng, Chen Yuan, Wang Zhengwang, Ge Xinyu, Wu Junqing, Chen Long, Lu Yipin, Xu Peng, Yao Jie

Abstract excerpt

Background: Immune cells play a crucial role in the development and progression of pancreatic cancer, yet the causal relationship remains uncertain due to complex immune microenvironments and conflicting research findings. Mendelian randomization (MR), this study aims to delineate the causal relationships between immune cells and pancreatic cancer while identifying intermediary factors. Methods: The genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38933268
DOI: 10.3389/fimmu.2024.1402113
PMCID: PMC11199692

Genes

CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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