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Article

Association between human blood metabolome and the risk of breast cancer.

Breast cancer research : BCR - 24 Jan 2023

Wang Yu, Liu Fanghua, Sun Lulu, Jia Yiming, Yang Pinni, Guo Daoxia, Shi Mengyao, Wang Aili, Chen Guo-Chong, Zhang Yonghong, Zhu Zhengbao

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer among women with limited treatment options. To identify promising drug targets for breast cancer, we conducted a systematical Mendelian randomization (MR) study to screen blood metabolome for potential causal mediators of breast cancer and further predict target-mediated side effects. METHODS: We selected 112 unique blood metabolites from 3 large-scale European...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36694207
DOI: 10.1186/s13058-023-01609-4
PMCID: PMC9872401

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