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Article

Genetically predicted blood metabolites mediate the association between circulating immune cells and pancreatic cancer: A Mendelian randomization study.

The journal of gene medicine - 1 May 2024

Zhao Guo, Cai Yuanting, Wang Yuning, Fang Yuan, Wang Shuhang, Li Ning

Abstract excerpt

BACKGROUND: Pancreatic cancer is characterized by metabolic dysregulation and unique immunological profiles. Nevertheless, the comprehensive understanding of immune and metabolic dysregulation of pancreatic cancer remains unclear. In the present study, we aimed to investigate the causal relationship of circulating immune cells and pancreatic cancer and identify the blood metabolites as potential mediators....

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38757222
DOI: 10.1002/jgm.3691

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