Article
Integrative analysis of serum lipids and chronic gastritis: causal insights from mendelian randomization and experimental models.
Lipids in health and disease - 22 Nov 2025
Chu Xinqiao, Biao Yaning, Li Hongzheng, Chen Jian, Yin Jixiong, Gao Xingxing, Wang Shaoli, Ma Jizheng, Yi Liufeng, Zhang Yixin, Zhang Muqing, Liu Zhen
Abstract excerpt
BACKGROUND: Lipid metabolism may be linked to chronic gastritis, but its causal role remains unclear. While current research emphasizes inflammation, mucosal changes, immune regulation, genetics, and the gut microbiota, the contribution of lipid metabolism is understudied. This study aims to evaluate the impact of serum lipids and the mechanistic roles of lipid-lowering drug targets in chronic gastritis. METHODS:...
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