Exploring the association between gastroesophageal reflux disease and hyperlipidemia through bioinformatics and Mendelian randomization.

Abstract excerpt

Observational research has found a relationship between gastroesophageal reflux disease (GERD) and hyperlipidemia (HLP). This study explored the relationship between GERD and HLP using bioinformatics and Mendelian randomization (MR) methods. We first conducted bioinformatics analyses to identify differentially expressed genes (DEGs) from disease datasets and then performed a two-sample MR analysis with aggregated...

Topics

• Gastroesophageal Reflux
• Humans
• Mendelian Randomization Analysis
• Hyperlipidemias
• Genome-Wide Association Study
• Computational Biology