Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional Mendelian randomization and colocalization analysis of gut microbiota on lipid profile.

Computational biology and chemistry - 1 Aug 2025

Cui Yu, Chen Yanzhu, Hu Mengting, Zhou He, Guo Jiarui, Wang Qijia, Xu Zaihua, Chen Liyun, Zhang Wancong, Tang Shijie

Abstract excerpt

The gut microbiota plays a crucial role in human health, but its impact on lipid metabolism remains unclear. Understanding the causal relationship between gut bacteria and lipid profiles is essential for developing strategies to prevent and treat dyslipidemia and cardiovascular diseases. This study aimed to assess this relationship using two-sample Mendelian randomization (MR). Data for both exposure and outcomes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gastrointestinal Microbiome
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Metabolism

Share to Lipids

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 40080991
DOI: 10.1016/j.compbiolchem.2025.108422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional Mendelian randomization and colocalization analysis of gut microbiota on lipid profile.PMID 40080991Read ↗

Type 1 diabetes mellitus, hyperlipidemia, and inflammatory bowel disease: a Mendelian randomization studySemantic proximity Read ↗

A Two-Sample Mendelian Randomization Analysis Investigates Associations Between Gut Microbiota and DyslipidemiaSemantic proximity Read ↗

Causal Associations between Gut Microbiota and Different Types of Dyslipidemia: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Causality of the gut microbiome and atherosclerosis-related lipids: a bidirectional Mendelian Randomization studySemantic proximity Read ↗

Effect of the gut microbiome, plasma metabolome, peripheral cells, and inflammatory cytokines on obesity: a bidirectional two-sample Mendelian randomization study and mediation analysisSemantic proximity Read ↗

Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization studySemantic proximity Read ↗

Mendelian randomisation analysis for intestinal disease: achievement and futureSemantic proximity Read ↗

Assessment of the causal relationship between gut microbiota and cardiovascular diseases: a bidirectional Mendelian randomization analysisSemantic proximity Read ↗

Unveiling the influence of lipidomes on inflammatory bowel disease: a bidirectional mendelian randomization studySemantic proximity Read ↗

Mendelian randomization analysis revealed causal effects from gut microbiota to abdominal obesitySemantic proximity Read ↗

Elucidating the causal relationship between gut microbiota, metabolites, and diabetic nephropathy in European patients: Revelations from genome-wide bidirectional mendelian randomization analysisSemantic proximity Read ↗

Causal associations between gut microbiome and cardiovascular disease: A Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.