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Article

Clonal megakaryocyte dysplasia with normal blood values: a covert, thrombosis-prone, early myeloproliferative neoplasm.

Haematologica - 1 Apr 2026

Barosi Giovanni, Rosti Vittorio, Campanelli Rita, Massa Margherita, Abbà Carlotta, Carolei Adriana, Catarsi Paolo, Inzoli Alessandro, Pergola Lorena, Barbui Tiziano, Tatarelli Caterina, Finazzi Maria Chiara, Condorelli Annalisa, Salmoiraghi Silvia, Rambaldi Alessandro, Gianatti Andrea, De Stefano Valerio, Gallì Anna, Gandossini Martina, Bardelli Michela, Gale Robert Peter, Malcovati Luca

Abstract excerpt

To improve our knowledge on the epidemiological, clinical and pathobiological profile of clonal megakaryocyte dysplasia with normal blood values (CMD-NBV), a BCR::ABL-negative myeloproliferative neoplasms clinical variant, we here report a series of 30 consecutive subjects with CMD-NBV. Sixteen subjects were men and the median age was 48 years (interquartile range [IQR], 39-53 years). A situation-driven diagnosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41262049
DOI: 10.3324/haematol.2025.288681
PMCID: PMC13040162

Genes

ASXL1
DNMT3A
NF1
TET2
ABL1
BCR
CSF3R
CUX1
KIT
RUNX1
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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