Article
Characterization of myeloproliferative neoplasms in the paediatric and young adult population.
British journal of haematology - 1 May 2023
Harris Zoey, Kaizer Hannah, Wei Aria, Karantanos Theodoros, Williams Donna M, Chaturvedi Shruti, Jain Tania, Resar Linda, Moliterno Alison R, Braunstein Evan M
Abstract excerpt
The aim of this study was to compare the genomic features and clinical outcomes between paediatric and young adult patients (PAYA, <40 years) and older adults (OA, ≥40 years) with myeloproliferative neoplasms (MPN) to gain insight into pathogenesis, disease prognosis and management. Of 630 MPN patients, 171 (27%) were PAYA with an average age at diagnosis of 31 years. Females were more prevalent in PAYA than OA...
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